A 20th Century pilot named Buck Rogers and his young friend Buddy Wade awake from 500 years in suspended animation to find that the world has been taken over by the outlaw army of Killer Kane.

Western settlers are being driven off their homesteads and ranches by a combination of Indian raids and attacks by bands of mysterious outlaws. The government sends out famed Indian scout Kit Carson and army officer David Brent to investigate, and Carson discovers that a villain named Pegleg controls an outlaw gang called the Black Raiders, and is using them and the Indians to drive out the settlers so he can establish his own empire. He determines to set a trap to expose the identity of Pegleg while avoiding traps and ambushes that Pegleg is setting for him.

Three government aviators called the "Flying G-Men", one of whom is disguised as "The Black Falcon", fight to protect the US and its allies from an enemy spy ring and to avenge the death of the fourth Flying G-Man.

An expedition arrives on an uncharted jungle island to rescue the local natives, led by a jungle boy, from a volcano that is about to erupt.