Produced at the same time as the more well-known The Twilight Zone (1959), this series was an extension of the tradition of radio horror and supernatural dramas such as Light's Out, The Mysterious Traveler and The Witches Tale. As with the Twilight Zone and the radio programs each tale was book-ended by an introduction and conclusion by a host. However, rather than creating fictional stories with supernatural twists and turns, this program sought out "real" stories of the supernatural, including ghosts, disappearances, monsters and the like, re-creating them for each episode. No solutions to these mysteries were ever found, and viewers could only scratch their heads and wonder, "what if it's real?"

A gang of street kids work with the FBI in their attempt to find and rescue their leader's father, a scientist who has been kidnapped by a terrorist group.

A 14-episode serial in which Mala, a Polynesian in the employ of U.S. Intelligence investigates sabotage on Clipper Island. A gang of spies causes the eruption of a volcano, for which our hero is blamed. He convinces the local Princess Melani of his innocence and helps her ward off a takeover by rival high priest Porotu.

Strategic targets on Earth are being destroyed by an unknown weapon. Government security head Henderson suspects it's an "atomic ray" originating from the moon! He assigns Commando Cody, scientist and man of action with a secret flying suit, to investigate. Soon, Cody is battling Earth thugs in the pay of Krog the moon man and making trips in his experimental rocket to the moon itself, in a perilous and all but singlehanded effort to thwart the planned invasion of Earth.

American adventurer Richard Grant is falsely accused of murdering an Indian noble and escapes to Africa in search of diamond field and the real culprit.

Flash Gordon, Dale Arden and Dr. Zarkov return to the planet Mongo for an antidote to the Purple Death, which wreaking destruction on Earth. However, Ming the Merciless has other plans for them.

Enemy spies try to steal a new fighter plane.

A group of street kids battle a terrorist gang led by a Japanese spy.

Tom King Jr. seeks to discover who murdered his father, a Texas Ranger; the trail leads to a network of Axis spies.

Buck Sherman and Jake Jackson, a couple of evil carpetbaggers, illegally enter a Navajo reservation to prospect for gold and end up killing Aranho, the Navajos chief. Black Arrow, presumed Aranho's son, refuses to kill the Indian agent, Tom Whitney, in revenge, as demanded by Navajo law. Then, he is driven off the reservation for his reluctance to kill Whitney and decides to join forces with Pancho, Mary Brent and the agent to go in search of the men who killed the chief.

The Canadians have discovered a valuable substance called Compound X, which can cure infantile paralysis. When a country at war with Canada learns that Compound X also contains magnetic properties that could aid them in their warfare against the British, they send agents to infiltrate Canada and steal a large quantity of the substance. It's up to Sgt. King (Allan Lane) and his Mounties to track down the agents and put an end to their scheme.