The Eagle uses sky writing to make threats against a corporation. Nathan Gregory owns a traveling fairground and is thought to be the Eagle. Craig McCoy is a pilot who goes looking for the Eagle when Gregory turns up missing.

Professor Davidson and his niece Diana Palmer search Africa for the Lost City of Zoloz, reputed to be the source of a large hidden treasure. Also searching is a local crook, Singapore Smith, and Dr. Max Bremmer, who plans to destroy the peace in which the native tribes have been living. However, Godfrey Prescott, otherwise known as the Phantom, is feared and respected by the natives and is able to circumvent the traps and schemes of the villains.

Produced at the same time as the more well-known The Twilight Zone (1959), this series was an extension of the tradition of radio horror and supernatural dramas such as Light's Out, The Mysterious Traveler and The Witches Tale. As with the Twilight Zone and the radio programs each tale was book-ended by an introduction and conclusion by a host. However, rather than creating fictional stories with supernatural twists and turns, this program sought out "real" stories of the supernatural, including ghosts, disappearances, monsters and the like, re-creating them for each episode. No solutions to these mysteries were ever found, and viewers could only scratch their heads and wonder, "what if it's real?"

Tom Wayne rescues Clancy, Renard and Schmidt in the Arabian desert and they join him in going after El Shaitan, a bad guy who is never seen as he tries to wipe out the Foreign Legion.

A newspaper publisher and his Korean servant fight crime as vigilantes who pose as a notorious masked gangster and his aide.

Captain Dan Tempest was an ex-pirate who received a pardon from the King and turned privateer after his stronghold of New Providence was taken over by Crown soldiers. Tempest and Lt. Beamish, the Crown-appointed deputy governor, were uneasy allies, fighting the Spanish privateers who were ravaging the Caribbean.

New York City policewoman Casey Jones' assignment to fight crime often entails her going undercover in some of the seediest and most dangerous parts of the city.