The period is the 1820's and the first wagon train leaves Independence heading west to Santa Fe. In order to maintain his power, the ruthless Official at Santa Fe must not let them arrive and he sends out his men to stop them. The wagon train then has to endure repeated attacks but is aided by a mysterious rider that shoots singing arrows and rides a painted stallion.

A crime fighter known as The Spider battles a villain called The Octopus, who is out to sabotage America and install his own government.

This show featured four rotating stars, Charles Boyer, David Niven, Ida Lupino, and Dick Powell in individual episodes consisting of everything from comedy to drama.

New York City policewoman Casey Jones' assignment to fight crime often entails her going undercover in some of the seediest and most dangerous parts of the city.

The California-Yucatan Railroad, being built for the good of Mexico, is under siege by a gang of terrorists hoping to force its sale; no one can prove their connection to profiteer Marsden. Manuel Vega, aged co-owner, calls in the aid of his nephew James, great-grandson of the original Zorro. Alas, James seems more adept at golf than derring-do; but after he arrives, Zorro rides again! Can one black-clad man on horseback defeat a gang supplied with airplanes and machine guns?

Professor Davidson and his niece Diana Palmer search Africa for the Lost City of Zoloz, reputed to be the source of a large hidden treasure. Also searching is a local crook, Singapore Smith, and Dr. Max Bremmer, who plans to destroy the peace in which the native tribes have been living. However, Godfrey Prescott, otherwise known as the Phantom, is feared and respected by the natives and is able to circumvent the traps and schemes of the villains.